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A new Cochrane Review, published in the Cochrane Library today and presented at the ERS International Congress, has found evidence from randomised trials, that taking an oral vitamin D supplement in addition to standard asthma medication is likely to reduce severe asthma attacks. Asthma is a common chronic2 disease affecting about 300 million people worldwide. The symptoms of asthma include wheezing3, coughing, chest tightness and shortness of breath.
今天发表在Cochrane图书馆并在ERS国际大会上发表的一篇新的《Cochrane评论》发现，随机试验的证据表明，除了标准哮喘药物外，口服维生素D补充剂可能会减少严重哮喘发作。哮喘是一种常见的慢性疾病，影响着全世界约3亿人。哮喘的症状包括喘息、咳嗽、胸闷和呼吸急促。
Low blood levels of vitamin D have been linked to increased risk of asthma attacks in children and adults with asthma. There has been a growing interest in the potential role of vitamin D in asthma management because it might help to reduce upper respiratory infections, (such as the common cold) that can lead to exacerbations of asthma.
血液中维生素D水平低与哮喘儿童和成人哮喘发作风险增加有关。人们对维生素D在哮喘管理中的潜在作用越来越感兴趣，因为它可能有助于减少可能导致哮喘恶化的上呼吸道感染（如普通感冒）。
The researchers found that giving an oral vitamin D supplement reduced the risk of severe asthma attacks requiring hospital admission or emergency department attendance from 6% to around 3%.They also found that vitamin D supplementation reduced the rate of asthma attacks needing treatment with steroid tablets. These results are based largely on trials in adults. They also found that vitamin D did not improve lung function or day-to-day asthma symptoms, and that it did not increase the risk of side effects at the doses that were tested.
研究人员发现，口服维生素D补充剂可将需要住院或急诊的严重哮喘发作风险从6%降低到3%左右。他们还发现，补充维生素D可降低需要类固醇片治疗的哮喘发作率。这些结果主要基于对成年人的试验。他们还发现，维生素D不会改善肺功能或日常哮喘症状，在测试剂量下也不会增加副作用的风险。
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