1.What's the matter, Susan?
询问发生了什么事。还可以用What's wrong?What's up?
2.Does it have anything to do with you and Harry?
have sth to do with与……有关have nothing to do with与……无关
3.But I'm not so sure that I want to leave New York, you, and the rest of our family.
表示对某事不确定,用Not so sure.
4.In every marriage, sacrifices have to be made by one partner from time to time.
make sacrifices做牺牲。sacrifice sth for 为……牺牲……
5.I also have my daughter to consider.
我必须考虑我的女儿。还可以用I have to consider my daughter.
6.It's a once-in-a-life time offer, Harry.
once-in-a-life time offer表示一生难得一遇的。