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A routine CAT scan turns up a suspicious spot.
一项常规CAT扫描发现了可疑阴影。
Is it a benign lump?
这是个良性肿块?
Or a cancerous tumor?
还是恶性肿瘤?
In the case of lung spots, four out of five turn out to be harmless.
按照肺斑点所视,证明其十有八九是良性的。
Unfortunately, making that determination takes a long needle and a biopsy, which means a puncture wound in the chest and a risk of infection.
然而不幸的是,做出这个决定需要长针和活组织检查,这意味着胸部刺伤及感染的风险。
Leroy Hood and colleagues at Seattle's Institute for Systems Biology have devised a painless blood test that could eliminate the need for most biopsies.
而西雅图系统生物学研究所勒罗伊·霍德和同事们发明了一种无痛的血液测试,可以不需要进行大多数活检。
They identified 371 proteins that coat lung tumors or leak out of them.
他们发现了371种覆盖肺肿瘤或泄漏的蛋白质。
Then they looked at blood samples taken from people who had had lung biopsies.
然后他们观察人肺活检的血样。
A pattern emerged: 13 proteins were significantly higher or lower in patients who had lung cancer than in those whose lumps were benign.
结果显现:肺癌患者的13个蛋白质均明显高于或低于比那些良性的肿块。
The researchers tried the blood test on different patients, and found that when it gave an “all-clear” result, it was correct 90 percent of the time.
研究人员试图对不同的患者进行血液测试,结果发现发现当给出“全部合格”的结果, 有90%是正确的。
The work appears in the journal Science Translational Medicine.
这项研究已经在《科学转化医学》杂志上发表。
Indi, a diagnostics maker, is commercializing the blood test.
而一家诊断制造商英蒂正试图将这样的血液测试商业化。
Hood says the same approach should work for almost any disease—which could make diagnostics much less prickly.
霍德表示同样的方法应适用于几乎可以使诊断更棘手的任何疾病。
