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So you can see these are the ones
大家可以看到这些老鼠
They are fatter, they are unhealthy mice
这个老鼠要胖些 属于不健康的老鼠
And Rawl and Dollman in the commentary for that study
罗尔和道尔曼在对这项研究进行评论时指出
Kind of put it altogether here
放在这里了
So stress leads to glucocorticoids
压力会导致肾上腺糖皮质激素的上升
That can potentiate
而肾上腺糖皮质激素又会影响到
The sympathetic neuron and adipose tissue
交感神经和脂肪组织
Leading to the release of NPY
从而导致神经肽Y抗体水平的上升
And a proliferation of proadipocytes and adipogenesis
从而造成前脂肪细胞和脂肪形成速度的激增
And macrophage infiltration
造成巨噬细胞的浸润
Which is something I'm just highlighting here
这是我想强调的内容
Because it can be relevant to what I talk about towards the end
因为它和我最后要讲的内容相关
Which in turn can end in insulin resistance
这一些列变化反过来导致胰岛素抗性的产生
So there is a kind of complicated but verified pathway
所以压力导致肥胖
With respect to stress and potential biological mechanism to obesity
或者至少导致脂肪细胞生长的生物过程
Or at least adipose growth
是一个非常复杂而多变的过程
But how is sleep involved?
那么睡眠在这中间扮演了什么角色呢?
Again, this is kind of intuitive thing
这又是一个直觉的问题
I mean we know that individuals who are very high stressed
我们知道承受了巨大压力的个体
Stressed in work
例如工作压力
Have a difficult time sleeping
他们会难以入睡
You know, they don't fall asleep as quickly
他们入睡的时间不够快
They often can have fragmented sleep
他们的睡眠经常被打断
And less sleep continuity
连续睡眠的时间较短
And report that their quality of their sleep was poor
而且他们自述睡眠质量不高
In the same way
同样的
There is some evidence
有证据证明
That people who don't get enough sleep
睡眠不足的人
Certainly have changes in their mood
可能会出现情绪变化
But there's now an emerging laboratory evidence suggesting
现在有越来越多的试验证据证明
That individuals are even more sensitive to stress exposure
睡眠不足的个体对压力更为敏感
Some of this more comes from
一些证据来自于
Matt Walker's lab at UC Berkeley
加州伯克利分校的马特沃克的实验室
