评论
打印
Brainy Mice' May Lead to Better Cognitive Disorder Treatments
有了神奇力量，老鼠不再怕猫
According to a new study, by changing a gene in mice, researchers were able make them more intelligent and less susceptible to fear and anxiety.
最新研究发现，通过改变老鼠基因能够使其更加聪明，紧张感和焦虑感也会慢慢减弱。
Researchers believe their work could lead to new treatments for disorders that include cognitive declines,
研究人员认为这可能是治疗认知障碍疾病的新疗法，
such as Alzheimer's disease, schizophrenia and post-traumatic stress disorder.
比如说阿尔茨海默病(Alzheimer's disease），精神分裂和创伤后应激障碍等疾病。
The researchers altered genes in mice to inhibit PDE4B is present in many organs of vertebrates, including humans.
研究人员改变老鼠基因成功抑制磷酸二酯酶-4B(PDE4B)的活跃性，很多脊椎动物体内都含有这种酶，包括人类。
In behavioral tests, the mice whose genes had been learned faster, remembered events longer and solved complex exercises better than mice without the alteration.
在行为能力测试中，与普通老鼠相比，PDE4B-抑制老鼠的学习能力增强，记忆时间更长，更擅长完成复杂运动。
The PDE4B-inhibited mice also spent more time in open spaces, brightly lit spaces and displayed lower levels of fear in the presence of cat urine,
PDE4B-抑制老鼠多数时间会呆在空旷、灯光辉煌的空间，对猫尿的恐惧感也大幅度减弱，
as opposed to regular mice who displayed normal levels of fear at the potential of a cat nearby.
而普通老鼠则喜欢呆在黑暗封闭环境，对猫可能出没的区域也甚是恐惧。
