Mice were divided into four groups to examine different doses of the colour additive.
老鼠被分成四组以检验不同剂量的酒黄石效果
Tartrazine was given to a total of 60 mice
酒黄石分三种不同剂量摄入60只老鼠,
at three different doses plus one control group from where they were 5 weeks to 9 weeks old.
此外还有一对照组老鼠都是5周至9周大
The tartrazine was mixed and given as an oral tablet.
酒黄石与其他物质想混制成口服药片
After nine weeks researchers analyzed the mice's function and behaviour specifically
九周后研究者分析了老鼠的行为活动
looked at how long it would take for the mouse to turn over to its feet when it was placed on its back,
尤其观察当老鼠被躺着放置时,他们自己站起来所用的时长
how long it took for the mouse to bring its head up when placed upside down on an incline,
当老鼠被倾斜着倒置时他们抬起头所用时长
placing the mouse on a platform to determine its cliff avoidance
将其放在平板上观察其悬崖回避能力
and how the mouse swam and behaved when placed in water
将其放入水中时它们的游泳与反应状态
and a test to determine the mouse's sense of smell by evaluating exploratory behaviour.
通过其探究行为探究老鼠的嗅觉
The results of the study determined Tartrazine did not affect the mice's food intake
研究结果显示,酒黄石不会影响老鼠的进食体重,
or body weight and the litter size of the offspring birth rate were also not affected.
而且老鼠每窝的仔畜数也没有受到影响
It was determined that tartrazine affected the mice's exploratory behavoiur
据断定。酒黄石影响老鼠的探究能力
but was most significantly seen in juvenile mice
但在幼鼠中表现明显
which suggested that it would the most effect third generations.
且第三代幼鼠可能受到影响最大
Another finding was that tartrazine accelerated the mice's swimming ability especially with male mice.
另一发现是酒黄石会使老鼠游泳能力加强,尤其是雄鼠
Overall the three doses that were used in the study
总之,研究中这三种不同剂量的摄入
did not have any negative effects on reproduction and only a few effects on behaviour.
没有对其繁殖产生任何不良作用,仅对其行为产生一点影响
The dose level had the most significance in male mice which were the amounts that were greater than the recommended adequate intake.
如果摄入量比建议摄入量高的话,雄性老鼠受到的影响更大
Researchers determined that the levels of tartrazine humans consume would not produce any adverse effects.
研究者断定,人类食用的酒石黄量不会造成任何不良影响
Another research article that was mentioned in the study above published in 2007 in the Regulatory toxicology and pharmacology journal
这项研究于2007年发表在杂志《管制毒理学与药理学》上的另一篇文章
concluded that from prior research that tested tartrazine in mice for two years reported that
总结称先前长达两年的对老鼠食用酒石黄的探究显示
the occurrence of tumours and disease are not related to tartrazine in the diet.
肿瘤的发现与相关疾病和饮食中的酒黄石没有关系
Another finding from the study was that
这项研究中的另一个发现是
tartrazine was not absorbed by the body and was easily metabolized in the colon and excreted.
酒黄石不会被人体吸收,而是易在结肠处发生新陈代谢并被排出体外
Other various studies have also concluded that tartrazine has no carcinogenic effects
其他多项研究也得出结论,酒黄石没有致癌作用
and does not affect development or reproductive behaviours.
不会影响机体发展和繁殖行为
Currently tartrazine is considered safe by the FDA.
目前食药局认为酒黄石是安全的