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1.in charge of 负责；主管
He is in charge of the school work.
他负责学校工作。
He was in charge of overlooking prisoners.
他负责监视囚犯。
2.familiar to 熟悉的；亲近的
Your name is familiar to me.
你的名字我是熟悉的。
I think the themes that you will hear on Tuesday around noon will be very familiar to people that have watched the campaign.
我想，你星期二中午要听到的演讲主题，对那些一直在观看竞选活动的人来说，应该是相当熟悉的。
