In Britain today, one in three men will die of heart disease.在如今的英国，三分之一的人死于心脏病

die of:死于

Many people die of famine every year.

每年有很多人死于饥荒。

My grandpa died of hunger in the old days.

我爷爷在旧社会死于饥饿。

In spite of all the advances in medical technology,尽管人类的医疗技术取得了长足进展

in spite of:尽管

He do not wear a coat in spite of the cool weather.

虽然天气寒冷，他没有穿外套。

He do not wear a coat in spite of the cool weather.

虽然天气寒冷，他没有穿外套。

词义辨析:

despite，in spite of这些前置词或前置短语都含有“虽然，尽管”之意。

despite书面用词，指不受某事或某种原因的阻碍，语气轻于in spite of。

Despite all our efforts we still lost the game.

尽管我们尽了全力，我们还是输掉了比赛。

in spite of语气较强，可与despite换用，口语或书面语中均可使用。